Complete investigation was conducted darunavir in pregnant women. Animal studies have not revealed in darunavir toxic activity or a negative impact on reproductive function and fertility.
The combination of drugs ritonavir can be used during pregnancy only if the expected benefit of its application for future mother outweighs the potential risk to the fetus.
It is not known, primobolan depot side effects capable of whether darunavir passes into breast milk. Studies in rats have shown that the drug penetrates the milk. Given the possibility of HIV transmission through breast milk, as well as the risk of serious side effects in infants, linked to exposure to darunavir, HIV-infected women receiving , should refrain from breastfeeding.
Dosing and Administration
Inside. Preparation should always be given in combination with low dose ritonavir as a means of improving its pharmacokinetic properties, as well as in combination with other antiretroviral drugs.The ability to assign ritonavir should be considered prior to initiating therapy ritonavir. After initiation of therapy primobolan depot side effects patients do not need to modify or discontinue therapy without consulting with their physician.
Doses of 75 mg and 150 mg are designed for use in pediatric practice. In adults, in order to achieve therapeutic doses of dosage data requires receiving a large number of tablets that on the one hand makes it difficult to swallow, on the other – can cause allergic reactions due to increased revenues primobolan depot side effects auxiliary substances contained in the tablets, so they should be used only when inaccessibility of other dosages .